Creamy, cheesy, and a little spicy—this rotini recipe is everything a comfort dish should be. The spiral pasta soaks up a rich, velvety Velveeta sauce that clings to every twist and turn. At the heart of it all? Juicy Cajun-spiced ground beef that delivers bold Southern flavor with every bite. Then, a blanket of gooey mozzarella melts over the top, pulling it all together into one irresistible plate.

Whether you’re cooking for a busy weeknight or impressing at a potluck, this dish checks all the boxes: fast, flavorful, and totally satisfying. It’s the kind of meal that turns ordinary evenings into something worth sitting down for.

What Kind of Pasta Should I Use for Creamy Mozzarella Rotini with Spicy Cajun Beef and Velveeta Sauce?

Rotini is the perfect choice for this dish because its spirals trap every drop of the creamy cheese sauce and spicy beef, ensuring maximum flavor in every bite. If you’re in a pinch, penne or cavatappi can also work, but rotini remains king for texture and sauce-capturing ability.

Ingredients for the Creamy Mozzarella Rotini with Spicy Cajun Beef and Velveeta Sauce

Rotini Pasta – The spiral shape is ideal for catching all that cheesy sauce and hearty beef.
Ground Beef – Lean ground beef brings a rich, savory flavor and a satisfying meaty bite.
Cajun Seasoning – This is what gives the beef its spicy kick and Southern charm.
Velveeta Cheese – Smooth, creamy, and ultra-melty—Velveeta is the backbone of the luscious sauce.
Mozzarella Cheese – Adds a stretchy, gooey finish on top for that irresistible cheese pull.
Heavy Cream or Milk – Thins out the Velveeta slightly to make a silky sauce.
Garlic Powder & Onion Powder – For extra depth and flavor.
Salt & Pepper – Essential for balance.
Fresh Parsley (optional) – A bright garnish that adds a hint of freshness.

How To Make the Creamy Mozzarella Rotini with Spicy Cajun Beef and Velveeta Sauce

Step 1: Cook the Pasta

Boil a large pot of salted water. Add rotini and cook until al dente, according to package directions. Drain and set aside.

Step 2: Brown the Beef

In a large skillet over medium heat, cook the ground beef until browned. Drain excess grease. Season with Cajun seasoning, garlic powder, onion powder, salt, and pepper.

Step 3: Make the Cheese Sauce

Lower the heat and stir in cubed Velveeta cheese and a splash of heavy cream or milk. Stir continuously until the cheese melts into a smooth, creamy sauce.

Step 4: Combine Pasta and Sauce

Add the drained rotini to the skillet with the cheese sauce and stir well to coat the pasta evenly.

Step 5: Top with Mozzarella and Broil

Sprinkle shredded mozzarella over the top. Optional: place the skillet under a broiler for 1-2 minutes to melt and lightly brown the cheese.

Step 6: Garnish and Serve

Finish with a sprinkle of chopped fresh parsley and a touch of crushed red pepper if you want a spicier finish.

How to Serve and Store Creamy Mozzarella Rotini with Spicy Cajun Beef and Velveeta Sauce

This pasta dish is best served hot right out of the skillet while the mozzarella is still gooey. For storing, let leftovers cool, then transfer to an airtight container and refrigerate for up to 4 days. Reheat in the microwave or on the stovetop with a splash of milk to loosen the sauce.

What to Serve With Creamy Mozzarella Rotini?

Garlic Bread

Crunchy, buttery garlic bread is the ultimate dipping companion for this cheesy dish.

Caesar Salad

A crisp Caesar salad adds a fresh, tangy balance to the richness of the pasta.

Roasted Broccoli

The slight char and bitterness of roasted broccoli play perfectly with the creamy sauce.

Cajun Shrimp Skewers

Amp up the Southern flavor with some quick Cajun shrimp on the side.

Pickled Jalapeños

If you’re a spice lover, add a few pickled jalapeños on the side for a fiery contrast.

Cornbread Muffins

Soft, sweet cornbread muffins offer a comforting Southern touch.

Simple Cucumber Salad

Cool and crunchy cucumbers with a vinegar kick help cleanse the palate.

Sweet Tea or Lemonade

Balance the spice with a refreshing Southern-style drink.

Want More Pasta Ideas with a Kick?

If you love this Creamy Mozzarella Rotini, check out these bold and flavorful meals:

Stovetop Creamy Ground Beef Pasta for quick weeknight comfort.
Creamy Beef and Shells Recipe when you’re craving rich, velvety sauce.
Cheesesteak Tortellini in Rich Provolone Sauce for that Philly twist.
Creamy Ground Beef Alfredo Pasta if you’re into creamier alfredo vibes.
One-Pot Smoked Sausage Pasta for a smoky, savory delight.

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And let me know in the comments how it turned out. Did you go extra spicy? Did you try it with shrimp or sausage instead?

I love seeing the twists you add. Got questions? Drop them below—we’re building a cozy kitchen community here.

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